Cocaine-induced myocardial injury seen as multiple mid-wall foci of late enhancement by contrast-enhanced cardiac magnetic resonance imaging

Buchholz, Stefan, Grieve, Stuart M., Maher, Richard, and Figtree, Gemma A. (2010) Cocaine-induced myocardial injury seen as multiple mid-wall foci of late enhancement by contrast-enhanced cardiac magnetic resonance imaging. European Heart Journal, 31 (11). p. 1422.

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Abstract

[Extract] A previously well 26-year-old man presented with severe retrosternal chest pain. There were no associated symptoms, and no relationship of the pain to inspiration, exertion, or posture. He was a frequent user of cocaine, most recently 48 h prior to presentation. Initial cardiac enzymes were substantially elevated [creatine kinase level 710 U/L (normal range 40–300 U/L) and troponin I 10.3 mg/L (normal value ,0.14 mg/L)] but rapidly returned to normal values. Twelve-lead electrocardiogram showed biphasic T-waves in the inferolateral leads. Computed tomography of the coronary and pulmonary arteries was normal. Cardiac magnetic resonance (CMR) imaging performed the day after presentation demonstrated normal left ventricular function with no evidence of regional wall motion abnormality, pericardial effusion, or pericardial enhancement on late gadolinium imaging. However, there were multiple foci of mid-wall and subepicardial late enhancement (LE) in the apical septum and apical lateral wall consistent with myocardial infarction or fibrosis.

Item ID: 34775
Item Type: Article (Case Study)
Keywords: myocardial injury, MRI, cocaine
ISSN: 1522-9645
Date Deposited: 16 Sep 2014 06:15
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
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