DNA vaccines: a modern-day vaccine revolution

Baird, Fiona J., Taki, Aya C., Lopata, Andreas L., and Smooker, Peter M. (2011) DNA vaccines: a modern-day vaccine revolution. In: Villanueva, Christian J., (ed.) Immunogenicity. Nova Science Publishers, New York, NY, USA, pp. 153-187.

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Abstract

DNA vaccination, or genetic immunisation, has progressed from initial observations 20 years ago through to commercial reality today. Along the way, there have been some stunning successes, including the first experimental vaccination of American condors, to protect them from devastation by the West Nile virus, through to the commercialization of the West Nile viral vaccine for use in horses. Along the way, a large number of research publications have detailed the uses of DNA vaccination as an attempted prophylactic and therapeutic strategy. This chapter will review the short history of DNA vaccination, the underlying immunology and technology, and some of the current and future applications of this revolutionary vaccination technique.

Item ID: 34374
Item Type: Book Chapter (Research - B1)
ISBN: 978-1-61761-591-7
Keywords: DNA vaccine, allergy, IgE antibody, allergen, immunology, immune responses, malaria, cancer
Date Deposited: 18 Aug 2014 00:16
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110701 Allergy @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics) @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 100%
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