Identification and quantification of specific IgG antibodies

Lopata, Andreas L. (2007) Identification and quantification of specific IgG antibodies. Current Allergy and Clinical Immunology, 20 (2). pp. 85-86.

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[Extract] Allergic diseases represent increasing health problems worldwide, and symptoms may not be easily distinguished from other disorders. The term hypersensitivity is defined as a reaction that induces reproducible symptoms and signs, initiated by exposure to a defined stimulus at a dose tolerated by normal subjects. Hypersensitivity can be differentiated into IgE and non-IgE allergic hypersensitivity as well as non-allergic hypersensitivity, which does not involve the immune system. Most patients are sensitised to more than one allergen which might trigger clinical symptoms, and often it is difficult to identify the major allergen. In addition, the presenting symptoms are dependent on current inflammation, presence of infection, physical and psychological stress and hormonal influences. Different tests may be used to distinguish between these conditions. An allergic hypersensitivity is usually IgE-mediated but may involve IgG antibodies. In this article we explore currently available tests and highlight their applications and limitations.

Item ID: 34360
Item Type: Article (Short Note)
ISSN: 1609-3607
Keywords: food allergy, IgG antibody; allergen; Streptavidin ImmunoCAP; pigeons; immunology
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Date Deposited: 12 Aug 2014 03:07
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110701 Allergy @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics) @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 100%
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