A preliminary investigation of serological tools for the detection of Onchocerca lupi infection in dogs

Giannelli, Alessio, Cantacessi, Cinzia, Graves, Patricia, Becker, Luke, Campbell, Bronwyn Evelyn, Dantas-Torres, Filipe, and Otranto, Domenico (2014) A preliminary investigation of serological tools for the detection of Onchocerca lupi infection in dogs. Parasitology Research, 113 (5). pp. 1989-1991.

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Abstract

Onchocerca lupi is a neglected filarioid causing nodular lesions associated with acute or chronic ocular disease in dogs. Despite the recent appraisal of its zoonotic potential, human cases are increasingly reported in the Old and New Worlds. Therefore, the development of accurate tools for the rapid diagnosis of O. lupi infections in dogs is becoming a priority. In this study, we conducted a preliminary investigation aimed at evaluating the usefulness of a commercially available ELISA test for the detection of O. lupi antigens in canine sera. The potential use of this tool for larger epidemiological studies of canine onchocerciasis is discussed.

Item ID: 33752
Item Type: Article (Research - C1)
ISSN: 1432-1955
Keywords: Onchocerca lupi, serology, dog, cross-reactivity, Og4C3, lymphatic filariasis
Date Deposited: 18 Jun 2014 09:30
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110803 Medical Parasitology @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 100%
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