Gilhotra, Rajit A., Malabu, Usman H., Manickam, Valli, Kan, George, and Sangla, Kunwarjit S. (2013) Prevalence and risk factors for non-traumatic amputation of lower limbs in subjects with end-stage renal failure on hemodialysis in north Queensland. In: Abstracts from the Inaugural Sydney Diabetic Foot Conference. p. 16. From: Inaugural Sydney Diabetic Foot Conference, 30-31 May 2013, Sydney, NSW, Australia.

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Abstract

BACKGROUND: Data from Northern Queensland have shown high rate of diabetes and end stage renal failure (ESRF) 1; both conditions are known to lead to limb amputation2. In spite of these no study has been published that analyses the magnitude and risk factors for amputation in the sub-population.

OBJECTIVES: The aims of the study was to document prevalence and identify risk factors of non-traumatic lower limb amputations in subjects treated with renal dialysis for chronic renal failure in North Queensland.

METHODS: All subjects diagnosed to have ESRF who attended the Townsville Regional Hospital Dialysis Centre from 01/01/2008 till date, were retrospectively studied. Odds ratio and χ2 tests were performed to identify variables most strongly associated with amputation.

RESULTS: We identified 8.8% prevalence of lower limb amputation in 114 subjects with ESRF on dialysis at our centre. The major risk factors of amputations in the cohort were indigenous background (Odds Ratio 0.2 [95% CI 0.03-1.2] P=0.007) and the presence of diabetes (Odds Ratio 1.9 [95% CI 1.62-2.3] P=0.003). Other variables were tested but fell short of statistical significance, these include: smoking history, gender and type of renal dialysis.

CONCLUSION: Indigenous Australians with diabetes mellitus on renal dialysis are at risk of having lower limb amputations. Primary prevention of diabetes in the sub-population may help in reducing the limb loss. Further prospective studies on a larger population are needed to confirm our findings.

Item ID:	30079
Item Type:	Conference Item (Abstract / Summary)
Date Deposited:	19 Mar 2014 04:49
FoR Codes:	11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110306 Endocrinology @ 100%
SEO Codes:	92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920104 Diabetes @ 100%
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