Melioidosis: an uncommon but also under-recognized cause of pneumonia in Papua New Guinea

Warner, Jeffrey M., Pelowa, Daniel B., and Currie, Bart J. (2010) Melioidosis: an uncommon but also under-recognized cause of pneumonia in Papua New Guinea. Papua New Guinea Medical Journal, 53 (3-4). pp. 176-179.

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Abstract

Melioidosis is being increasingly recognized as an important cause of severe, acute community-acquired pneumonia in various tropical regions. The chronic form of melioidosis can also mimic tuberculosis. Studies have established that, while uncommon in the Port Moresby region, melioidosis is an important cause of pneumonia and sepsis in the Balimo region of Western Province. Phylogenetic analyses of strains of Burkholderia pseudomallei from Papua New Guinea have shown them to be more closely related to strains of B. pseudomallei from Australia than to strains from Southeast Asia. This is consistent with the proposed origins of B. pseudomallei in Australia, with subsequent spread out of Australia to Southeast Asia during the last ice age. Further surveillance across Papua New Guinea is likely to unmask other locations where B. pseudomallei occurs in the environment and where melioidosis is currently not being diagnosed.

Item ID: 29560
Item Type: Article (Research - C1)
ISSN: 0031-1480
Related URLs:
Funders: Australian National Health and Medical Research Council (NHMRC)
Projects and Grants: Project Grant no. 383504, Project Grant no. 605820
Date Deposited: 30 Oct 2013 02:46
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1108 Medical Microbiology > 110801 Medical Bacteriology @ 80%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110308 Geriatrics and Gerontology @ 20%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 80%
92 HEALTH > 9205 Specific Population Health (excl. Indigenous Health) > 920506 Rural Health @ 20%
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