Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs

Dantas-Torres, Filipe, Capelli, Gioia, Giannelli, Alessio, Ramos, Rafael Antonio Nascimento, Lia, Riccardo Paolo, Cantacessi, Cinzia, de Caprariis, Donato, De Tommasi, Anna Sara, Latrofa, Maria Stefania, Lacasella, Vita, Tarallo, Viviana Domenica, Di Paola, Giancarlo, Qurollo, Barbara, Breitschwerdt, Edward, Stanneck, Dorothee, and Otranto, Domenico (2013) Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs. Parasites & Vectors, 6. 245. pp. 1-8.

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Abstract

Background: Tick-borne diseases comprise a group of maladies that are of substantial medical and veterinary significance. A range of tick-borne pathogens, including diverse species of bacteria and protozoa, can infect both dogs and humans. Hence, the control of tick infestations is pivotal to decrease or prevent tick-borne pathogen transmission. Therefore, different commercial products with insecticidal, repellent or both properties have been developed for use on dogs. Recently, a collar containing a combination of imidacloprid 10% and flumethrin 4.5% has proven effective to prevent tick and flea infestations in dogs under field conditions and the infection by some vector-borne pathogens they transmit under laboratory-controlled conditions.

Methods: From March 2011 to April 2012, a field study was conducted in a private shelter in southern Italy to assess the efficacy of the imidacloprid/flumethrin collar against tick and flea infestations and to determine if this strategy would decrease tick-borne pathogen transmission in young dogs. A total of 122 animals were enrolled in the study and randomly assigned to group A (n = 64; collared) or group B (n = 58; untreated controls). Dogs were examined monthly for ticks and fleas and systematically tested for selected tick-borne pathogens.

Results: Compared to controls, the collar provided overall efficacies of 99.7% and 100% against tick and flea infestation, respectively. The overall efficacy for the prevention of tick-borne pathogens (i.e., Anaplasma platys and Babesia vogeli) was 91.6%.

Conclusions: This study demonstrates that the imidacloprid/flumethrin collar is efficacious against flea and tick infestation as well as tick-borne pathogen transmission to dogs under field conditions.

Item ID: 29506
Item Type: Article (Research - C1)
ISSN: 1756-3305
Keywords: canine vector-borne diseases, Anaplasma platys, Babesia vogeli, Hepatozoon canis, prevention, dog, imidacloprid, flumethrin, tick
Additional Information:

© 2013 Dantas-Torres et al.; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Date Deposited: 25 Sep 2013 05:25
FoR Codes: 07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070708 Veterinary Parasitology @ 40%
06 BIOLOGICAL SCIENCES > 0605 Microbiology > 060502 Infectious Agents @ 30%
11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111501 Basic Pharmacology @ 30%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences @ 30%
92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 70%
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