Making Bispirin: synthesis, structure and activity against Helicobacter pylori of bismuth(III) acetylsalicylate

Andrews, Philip C., Blair, Victoria L., Ferrero, Richard L., Junk, Peter C., and Kumar, Ish (2013) Making Bispirin: synthesis, structure and activity against Helicobacter pylori of bismuth(III) acetylsalicylate. Chemical Communications, 49 (28). pp. 2870-2872.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: http://dx.doi.org/10.1039/c3cc40645h
 
15
6


Abstract

Reaction of Bi((OᵗBu)₃ with aspirin (acetylsalicylic acid = aspH) in dry toluene results in the bismuth(III) complex, [Bi(O₂C(C₆H₄)OAc)₃]∞ 1 (O₂C(C₆H₄)OAc = asp), minimum inhibitory concentration (MIC) against Helicobacter pylori >= 6.25 mu g mL⁻¹), while the inclusion of a stoichiometric equivalent of (KOᵗBu)leads to crystals of the bismuthate salt [KBi(O₂C(C₆H₄)OAc)₄]∞ 2.

Item ID: 28353
Item Type: Article (Research - C1)
ISSN: 1364-548X
Keywords: bismuth, helicobacter pylori, salicylate
Date Deposited: 17 Jul 2013 05:25
FoR Codes: 03 CHEMICAL SCIENCES > 0302 Inorganic Chemistry > 030204 Main Group Metal Chemistry @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
Downloads: Total: 6
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page