Basophil activation assays

Lopata, Andreas L. (2008) Basophil activation assays. Current Allergy and Clinical Immunology, 21 (3). pp. 146-147.

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Abstract

[Extract] Allergic diseases, including reactions to foods, represent increasing health problems worldwide, and symptoms may not always be easily distinguished from other disorders. Therefore, different tests should be used to support the diagnosis, and in allergic reactions to food, it is necessary to distinguish between an allergic and an adverse reaction. The gold standard for food allergy or intolerance is the double-blind placebo-controlled food challenge (DBPCFC). However, this technique does not distinguish between allergic and non-allergic reactions involving different antibody types, cellular immune mechanisms and reactions based on intolerance.

Item ID: 28329
Item Type: Article (Short Note)
ISSN: 1609-3607
Keywords: allergy, allergen, basophil assay
Funders: Medical Research Council of South Africa, National Research Foundation, South Africa
Date Deposited: 17 Jul 2013 09:27
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110701 Allergy @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics) @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 100%
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