Mucociliary clearance in ventilated adult patients: factors which may effect physiotherapy research

Jones, A., and Innes, N. (2008) Mucociliary clearance in ventilated adult patients: factors which may effect physiotherapy research. In: 2007 APA Conference Week Abstracts: cardiorespiratory physiotherapy Australia 10th biennial conference: merging education into practice (54) S8-S8. From: 2007 APA Conference Week: cardiorespiratory physiotherapy Australia 10th biennial conference: merging education into practice, 4-8 October 2007, Cairns, QLD, Australia.

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Abstract

Mucociliary clearance (MCC) is an important defence system, giving protection for the body against inhaled pathogens with the potential to incite infection. During mechanical ventilation patients often receive therapy with the premise that a deficiency in MCC exists. To effectively administer therapy to individuals receiving mechanical ventilation it is necessary to determine if a deficit in MCC is present. Physiotherapy research into treatment of ventilated patients tends to be inconclusive in determining if physiotherapy decreases complications, length of ventilation time and stay in ICU. By determining the factors which may affect MCC physiotherapy research can be better targeted to those populations which are shown to have decreased MCC. A literature review was undertaken of Medline and PEDro databases using key terms of mucociliary clearance, artificial airways, ventilated and mucoregulating. The search was limited to articles published within the last twelve years: eighty-seven articles were found which met the search strategy. MCC was found to depend upon cilia beat frequency, mucous rheology and load, and the properties of the periciliary fluid layer. Important factors which affect MCC include medications, temperature, air pressure, osmolarity, age, humidity, pH, high oxygen concentrations, disease state and sleep. When researching the effectiveness of physiotherapy techniques on adult ventilated patients, researchers should document and/or stratify for the factors noted above. This is likely to demonstrate that physiotherapy does decrease ventilator time, pulmonary complication rates and length of stay in ICU.

Item ID: 27913
Item Type: Conference Item (Abstract / Summary)
ISSN: 1445-8330
Keywords: physiotherapy, intensive care, mucociliary clearance
Date Deposited: 04 Jul 2013 00:19
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110399 Clinical Sciences not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9202 Health and Support Services > 920201 Allied Health Therapies (excl. Mental Health Services) @ 100%
Downloads: Total: 33
Last 12 Months: 3
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