Negative images in the fine needle aspiration cytologic diagnosis of mycobacterial infections

R. Iyengar, Krishnan, and Basu, Debdatta (2001) Negative images in the fine needle aspiration cytologic diagnosis of mycobacterial infections. The Malaysian Journal of Pathology, 23 (2). pp. 89-92.

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Abstract

Cytologic diagnosis of mycobacterial infection has conventionally depended on the recognition of granulomatous inflammation with caseous necrosis and the identification of acid-fast bacilli with special stains. Immunocompromised patients however may not mount the expected response. Mycobacteria can be seen as negative images in fine needle aspiration cytologic smears from patients with acquired immunodeficiency syndrome. We report the cytologic findings of lymphnode aspiration from four patients where the mycobacteria were seen in the routine May Grunwald Giemsa-stained smear as unstained rod-shaped structures in the background and within histiocytes. These were confirmed to be acid-fast bacilli with the Ziehl-Neelsen stain.

Item ID: 26559
Item Type: Article (Case Study)
ISSN: 0126-8635
Keywords: negative images, acquired immunodeficiency syndrome, mycobacterial infections, HIV infection, fine needle aspiration cytology
Date Deposited: 24 Jun 2013 04:15
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110316 Pathology (excl Oral Pathology) @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 50%
92 HEALTH > 9202 Health and Support Services > 920203 Diagnostic Methods @ 50%
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