Laboratory diagnosis of lymphatic filariasis in Australia: available laboratory diagnostic tools and interpretation

Joseph, Hayley, Speare, Richard, and Melrose, Wayne (2012) Laboratory diagnosis of lymphatic filariasis in Australia: available laboratory diagnostic tools and interpretation. Australian Journal of Medical Sciences, 33 (1). pp. 2-9.

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Abstract

Lymphatic filariasis (LF) is the second most common mosquito-borne parasitic disease globally and a leading cause of disability. Although LF is not endemic in Australia, individuals returning or emigrating from endemic areas can potentially be exposed to or infected with the filarial nematodes that cause LF, the most prevalent being Wuchereria bancrofti. Correct diagnosis requires an understanding of the parasite lifecycle, differences in distribution of the filarial species, and use of the most appropriate diagnostic tests. Since the physician typically does not specify the laboratory tests required to diagnose LF, laboratory scientists are usually responsible for choosing the most appropriate laboratory tests, and for their interpretation. Since there are a number of tests available to diagnose LF, and the choice of test is based on a number of factors including stage of the disease and the region visited, this review aims to clarify the likely tests which should be performed for diagnosis of LF in Australia.

Item ID: 26280
Item Type: Article (Research - C1)
ISSN: 1038-1643
Keywords: Lymphatic filariasis, diagnosis, ELISA, microfilaraemia, antigen, antibody
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Date Deposited: 11 Apr 2013 01:31
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 100%
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