An analysis of the creatine kinase isoenzyme and cardiac troponin T levels in a polymyositis patient

Golding, R.M. , Giles, L.G.F., and Sokoya, E.M. (2008) An analysis of the creatine kinase isoenzyme and cardiac troponin T levels in a polymyositis patient. American Journal of Immunology, 4 (1). pp. 1-7.

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Abstract

From an extensive model developed to interpret physiological processes we are able to show that the observed elevated creatine kinase-myoglobin (CK-MB) and serum concentration of cardiac troponin T (cTnT) values for a particular patient are associated with the inflammatory disease, polymyositis, and not myocardial injury. This highlights that caution must be exercised in using elevated CK-MB and cTnT levels as evidence for myocardial damage in patients with chronic muscle degeneration such as polymyositis.

Item ID: 25461
Item Type: Article (Refereed Research - C1)
Keywords: polymyositis; prednisolone; blood pressure; heart rate; erythrocyte sedimentation rate; creatine kinase isoenzyme, cardiac troponin T
ISSN: 1558-3775
Date Deposited: 25 Mar 2013 05:22
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110302 Clinical Chemistry (diagnostics) @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110316 Pathology (excl Oral Pathology) @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 50%
92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920116 Skeletal System and Disorders (incl. Arthritis) @ 50%
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