Human parvovirus B19: a literature review and case study

Smith, Jacqueline, and Whitehall, John (2008) Human parvovirus B19: a literature review and case study. Infant, 4 (3). 21. pp. 101-103.

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Human parvovirus is ubiquitous. It affects human erythroid precursors causing their lysis and apoptosis, resulting in varying degrees of interference with red cell production. There is a range of clinical presentation from no obvious abnormalities, to the classic 'slapped cheek' and lacy body rash in a child, to fever and arthropathy in an adult. The level of haemoglobin may fall by 20g/dL or more precipitating anaemia in susceptible people. Amongst the most susceptible are unborn babies who suffer from a high rate of abortion if affected in the first trimester, anaemia that may result in non-immune hydrops in the second trimester, and in utero death in the third trimester. An illustrative case study of hydrops in the second trimester treated by in utero transfusion is presented, with a review of the literature.

Item ID: 25174
Item Type: Article (Case Study)
ISSN: 1745-1213
Keywords: Parvovirus B19; infection; fetal anaemia; hydrops fetalis; in-utero transfusion ovale; cardiomegaly; anomalies
Date Deposited: 03 Mar 2013 22:28
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111403 Paediatrics @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1110 Nursing > 111003 Clinical Nursing: Secondary (Acute Care) @ 50%
SEO Codes: 92 HEALTH > 9202 Health and Support Services > 920210 Nursing @ 50%
92 HEALTH > 9205 Specific Population Health (excl. Indigenous Health) > 920501 Child Health @ 50%
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