Circulating bone marrow derieved osteo-progenitors in vasculature contributes towards vascular calcification

Pal, Shripad, Rush, Catherine, and Golledge, Jonathan (2009) Circulating bone marrow derieved osteo-progenitors in vasculature contributes towards vascular calcification. In: Journal of Vascular Research (46) p. 34. From: 14th Australian and New Zealand Microcirculation Society Meeting, 25-27 August 2009, Queenstown, New Zealand.

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Abstract

[Extract] Vascular calcification is an important determinant of cardiovascular mortality. The mechanisms responsible for vascular calcification are controversial. It has been suggested that the bone marrow derived osteo-progenitor population may contribute to the development of arterial mineralization. Osteocalcin expressing mononuclear cells (OCN+ MNCs) have recently been demonstrated within the circulation of adults and shown to have ability to carry out mineralization both in vitro and within mice. The aim of this study was to assess the association of vascular calcification with circulating bone marrow derived osteo-progenitors and stem cell mobilizing cytokines in two mice models and a human patient cohort.

Item ID: 25043
Item Type: Conference Item (Abstract / Summary)
ISSN: 1423-0135
Date Deposited: 20 Feb 2013 09:20
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1102 Cardiovascular Medicine and Haematology > 110201 Cardiology (incl Cardiovascular Diseases) @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920103 Cardiovascular System and Diseases @ 100%
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