Neuroendocrine disturbances in diabetes: role of hypothalamic regulatory peptides

Williams, Gareth, McCarthy, H. David, McKibbin, Pauline E., Malabu, Usman, and Leitch, Helen F. (1993) Neuroendocrine disturbances in diabetes: role of hypothalamic regulatory peptides. In: Shafrir, Eleazar, (ed.) Frontiers in Diabetes Research: biennial review volume 1992. Lessons From Animal Diabetes, 4 . Smith-Gordon, London, UK, pp. 203-217.

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[Extract] Diabetes has profound and far-reaching effects on many aspects of energy balance, hormone secretion and behaviour [1]. The hypothalamus, by virtue of its key position in controlling neuroendocrine and metabolic activities, is undoubtedly important in mediating these effects, but their mechanisms are largely unknown. A fuller understanding of the underlying neurotransmitter abnormalities will not only help to elucidate the basis of hypothalamic regulation, but may also be rewarded by the development of new treatments for several important problems in human diabetes.

Item ID: 23505
Item Type: Book Chapter (Research - B1)
ISBN: 978-1-85463-077-3
Keywords: diabetes, hypothalamus, regulatory peptides, neuropeptide Y, somatostatin, neurotensin, energy balance, pituitary
Date Deposited: 10 Sep 2014 04:39
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110306 Endocrinology @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920104 Diabetes @ 100%
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