Parallel Microflow Photochemistry: Process Optimization, Scale-up, and Library Synthesis
Yavorskyy, Alexander, Shvydkiv, Oksana, Hoffmann, Norbert, Nolan, Kieran, and Oelgemoeller, Michael (2012) Parallel Microflow Photochemistry: Process Optimization, Scale-up, and Library Synthesis. Organic Letters, 14 (17). pp. 4342-4345.
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DOI: 10.1021/ol301773r
View at Publisher Website: http://dx.doi.org/10.1021/ol301773r
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Abstract
A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5H)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis.
| Item ID: | 23358 |
|---|---|
| Item Type: | Article (Research - C1) |
| ISSN: | 1523-7052 |
| Date Deposited: | 09 Sep 2012 23:17 |
| FoR Codes: | 03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030503 Organic Chemical Synthesis @ 50% 03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030505 Physical Organic Chemistry @ 30% 03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030504 Organic Green Chemistry @ 20% |
| SEO Codes: | 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100% |
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