Buckingham, D. A., Keene, F. R., and Sargeson, A. M. (1973) Base Hydrolysis of Coordinated Acetonitrile. Journal of the American Chemical Society, 95 (17). pp. 5649-5652.

PDF (Published Version) - Published Version Restricted to Repository staff only

Abstract

The base hydrolysis of acetonitrile to acetamide is catalyzed by a factor of 2 X l0(6) on coordination to CO(NH3)5 8+. Hydroxide appears to attack the carbon atom of the nitrile group, while in a separate and concurrent process the methyl protons exchange. On addition of acid to the acetamido complex produced, protonation occurs on the carbonyl oxygen (pKa = 3.02; μ = 1.0 M, NaC104; T = 25°) rather than on the amide nitrogen atom.

Item ID:	22764
Item Type:	Article (Research - C1)
ISSN:	1520-5126
Date Deposited:	10 Sep 2012 03:41
FoR Codes:	03 CHEMICAL SCIENCES > 0302 Inorganic Chemistry > 030207 Transition Metal Chemistry @ 100%
SEO Codes:	97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
Downloads:	Total: 5
	More Statistics