Leiter, Ulrike, and Garbe, Claus (2011) In Reply: sentinel lymph node biopsy in melanoma. Annals of Surgical Oncology, 18 (2). pp. 598-599.

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Abstract

[Extract] Di Georgi and colleagues propose that sentinel lymph node biopsy (SLNB) does not provide a real survival benefit and that the disease-free survival benefit is a result of lead-time bias. These are old arguments that have been repeatedly discussed in the literature. A reiterative statement of these arguments does not make them truer. The only new idea in the letter of Di Georgi and colleagues is to designate the gain of disease-free survival time as lead-time bias that shows that they did not really understand the concept of lead time bias.

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