Deep microsporidial keratitis after keratoconjunctivitis

Badenoch , Paul R., Coster, Douglas J., Sadlon, Tania A. , Klebe, Sonja , Stirling, John W. , Jaunzems, Alvis E. , and Mazierska, Janina E. (2011) Deep microsporidial keratitis after keratoconjunctivitis. Clinical and Experimental Ophthalmology, 39 (6). pp. 577-580.

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[Extract] Microsporidia are intracellular pathogens of animals andhumans. Although not hyphal, a recent study suggests theyare fungi descended from an ancestral zygomycete. Theyhave a unique method for invading susceptible tissue: an internal coiled tube everts rapidly and sporoplasm moves into the cell as if through a hypodermic needle. In the human eye, microsporidial infection presents as keratoconjunctivitis or stromal keratitis. The former has been reported in HIV+ patients because of Encephalitozoon and in immunocompetent patients because of several genera. Stromal infection is seen in immunocompetent patients and is caused mostly by Vittaforma corneae. We report a case in which keratoconjunctivitis preceded deep stromal infection in a patient with a low neutrophil count.

Item ID: 19617
Item Type: Article (Case Study)
ISSN: 1442-9071
Keywords: microsporidium, Vittaforma corneae, cornea, keratitis, rRNA gene
Date Deposited: 21 Feb 2012 05:25
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1113 Ophthalmology and Optometry > 111301 Ophthalmology @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110199 Medical Biochemistry and Metabolomics not elsewhere classified @ 50%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920107 Hearing, Vision, Speech and Their Disorders @ 100%
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