Liquorice and canine Addison's disease

Jarrett, R.H., Norman, E.J., and Squires, R.A. (2005) Liquorice and canine Addison's disease. New Zealand Veterinary Journal, 53 (3). p. 214.

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[Extract] Hypoadrenocorticism, or Addison's disease, is an uncommon endocrinopathy of dogs (Feldman and Nelson 2004). Long-term management of affected dogs in New Zealand involves treatment with oral fludrocortisone acetate (Florinef tablets; Bristol-Myers Squibb (NZ) Ltd, Auckland, NZ), which is a relatively expensive synthetic adrenocortical steroid. Table salt may be added to the food, in an attempt to reduce the amount of fludrocortisone required. Despite fludrocortisone therapy, many Addisonian dogs remain hyponatraemic and hyperkalaemic and the required dose of fludrocortisone may need to be increased during the first year of treatment. Increasing the dose of fludrocortisone is not only expensive, but may also have undesirable effects through its potent glucocorticoid action.

Item ID: 18274
Item Type: Article (Short Note)
ISSN: 1176-0710
Date Deposited: 01 Sep 2011 04:36
FoR Codes: 07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070706 Veterinary Medicine @ 100%
SEO Codes: 86 MANUFACTURING > 8609 Veterinary Pharmaceutical Products > 860903 Veterinary Pharmaceutical Treatments (e.g. Antibiotics) @ 100%
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