Polyspecificity of autoimmune responses in type 1 (autoimmune) diabetes
Esteban, L.M., and Baxter, A.G. (2001) Polyspecificity of autoimmune responses in type 1 (autoimmune) diabetes. Clinical and Experimental Immunology, 126 (2). pp. 184-186.
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Abstract
Autoimmunity is, by definition, supposed to be antigen specific [1], yet for almost 50 years, associations have been recognized between different autoimmune diseases [2–5]. For example, the increased incidence of gastric and thyroid autoimmunity in type 1 diabetes was first reported in 1963 [6]. These associations are in addition to the occasional cases of the autoimmune polyglandular syndromes [7] and are found independently of chronic mucocutaneous moniliasis, which is characteristic of the Type I syndrome (APECED), and Addison's disease which invariably occurs in the Type II syndrome [8].
| Item ID: | 17252 |
|---|---|
| Item Type: | Article (Commentary) |
| ISSN: | 1365-2249 |
| Keywords: | autoimmune disease, type 1 diabetes, gastritis, systemic lupus erythematosus, thyroiditis, Grave's disease, Hashimoto's disease, Sjogren's syndrome |
| Additional Information: | Invited commentary |
| Date Deposited: | 12 Jul 2011 06:23 |
| FoR Codes: | 11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110706 Immunogenetics (incl Genetic Immunology) @ 100% |
| SEO Codes: | 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 100% |
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