Developing NKT cells need their calcium
Godfrey, Dale I., Stankovic, Sanda, and Baxter, Alan G. (2009) Developing NKT cells need their calcium. Nature Immunology, 10. pp. 231-233.
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DOI: 10.1038/ni0309-231
View at Publisher Website: http://dx.doi.org/10.1038/ni0309-231
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Abstract
Although the development of natural killer T cells is a T cell antigen receptor–dependent process, the signaling pathways involved are poorly defined. New data demonstrate that the calcineurin–transcription factor NFAT pathway exerts a critical influence on this process by controlling the transcription factor Egr2.
| Item ID: | 15691 |
|---|---|
| Item Type: | Article (Commentary) |
| ISSN: | 1529-2916 |
| Date Deposited: | 12 Jul 2011 04:03 |
| FoR Codes: | 11 MEDICAL AND HEALTH SCIENCES > 1107 Immunology > 110703 Autoimmunity @ 100% |
| SEO Codes: | 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920108 Immune System and Allergy @ 100% |
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