The efficacy and safety of human oocyte vitrification

Chang, Ching-Chien, Nagy, Zsolt Peter, Shapiro, Daniel B., Bernal, Diana Patricia, Kort, Hilton I., and Vajta, Gábor (2009) The efficacy and safety of human oocyte vitrification. Seminars in Reproductive Medicine, 27 (6). pp. 450-455.

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Abstract

Vitrification is now a widely applied and highly successful approach for cryopreservation in reproductive biology. Rapidly increasing data prove that it is also a highly efficient technique for low-temperature storage of human oocytes. The latest approaches with appropriately selected cryoprotectants, tools and techniques, and properly adjusted parameters allow close to 100% morphological survival rates, and in vitro embryo development, as well pregnancy and implantation rates, comparable with those achieved with fresh oocytes. With standardization of the technique and elimination of biosafety problems by preserving all the positive features, vitrification may become a common part of the everyday routine in a human embryo laboratory, and it may offer a solution for various medical and social situations as well as for simple logistic problems commonly occurring in assisted reproduction.

Item ID: 10932
Item Type: Article (Research - C1)
ISSN: 1526-4564
Keywords: cryopreservation; DMSO; vitrification; oocytes; sterile
Date Deposited: 06 May 2010 01:50
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111404 Reproduction @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920114 Reproductive System and Disorders @ 100%
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