Cryopreservation of human oocytes: hopes, no hypes?

Nagy, Zsolt Peter, Rienzi, Laura, and Vajta, Gabor (2009) Cryopreservation of human oocytes: hopes, no hypes? Expert Review of Obstetrics & Gynecology, 4 (6). pp. 585-587.

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The development of an efficient cryopreservation technique for human oocytes is probably the most important achievement in human assisted reproductive technology (ART) today. Although the first pregnancy from slow-rate frozen oocytes was reported 23 years ago by Chen, the overall efficiency has remained exasperatingly low and has resulted in the cessation of major clinical activity in this area for almost 20 years. Paradoxically, the first wave of advancement was the result of a law that was created to undermine certain advancement in human ART. Skilled and ambitious embryologists in Italy tried to find alternative ways to compensate the negative effects of the strict regulations and, thus, the efficiency of traditional freezing expanded considerably and achieved the level of clinical applicability. However, the breakthrough in the technology was provided by the alternative cryopreservation approach, vitrification.

Item ID: 10827
Item Type: Article (Editorial)
ISSN: 1747-4116
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Date Deposited: 30 Apr 2010 04:27
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111404 Reproduction @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920114 Reproductive System and Disorders @ 100%
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