Increasing glycaemic burden (GB) associated with diabetes in a UK Health District - a six year follow-up study

Khoo, E.Y.H., Harrison , R.F., Clayton , J.A., and Kennedy, R.L. (2005) Increasing glycaemic burden (GB) associated with diabetes in a UK Health District - a six year follow-up study. In: Papers from Diabetes UK Annual Professional Conference 2005 (22) p. 1. From: Diabetes UK Annual Professional Conference 2005, 20 - 22 April 2005, Glasgow, UK.

[img] PDF (Published Version)
Download (41kB)
View at Publisher Website:


GB is an integrated measure of hyperglycaemia over time and can be used to quantify risk of complications, and is useful in health economic projections. In a single Health District, we estimated the individual and total GB of diagnosed diabetes over 6 years. GB was calculated from over 91 000 HbA1c measurements between 1996 and 2001, and patients identified using linkage between 3 clinical databases. GB was expressed as months per HbA1c % above threshold of 7.0. Over the study period, diabetes increased from 2.8 % of the population to 5.12% – a 79% increase, while total GB increased by only 55%. Annual GB of individual new patients decreased from 14.7 (CI 13.1–16.3) to 7.9 (7.3–8.6). Among 5027 patients accessing structured care in 1996, average GB increased steadily. The major increase was amongst those initially treated with diet alone – GB 7.0 (6.4–7.7) to 10.1 (9.3–11.0), and with oral hypoglycaemics – 13.8 (13.0–14.5) to 15.9 (15.1–16.8). High GB was a strong predictor of hyperglycaemic emergency. Increased GB was due to treatment failure and increased diagnosis of type 2 diabetes. Effective early intervention would reduce the burden of the disease and decrease emergency admissions.

Item ID: 10200
Item Type: Conference Item (Poster)
ISSN: 1464-5491
Date Deposited: 08 Jul 2010 04:27
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1199 Other Medical and Health Sciences > 119999 Medical and Health Sciences not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
Downloads: Total: 242
Last 12 Months: 11
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page