Lennox-Bulow, Danica, Smout, Michael, Wilson, David, and Seymour, Jamie (2023) Inter-species variation in stonefish (Synanceia spp.) ichthyocrinotoxins; an ecological perspective. Toxicon, 221. 106977.

Piontek, Melissa, Andreosso, Athena, and Smout, Michael (2023) Rapid and permanent cytotoxic effects of venom from Chiropsella bronzie and Malo maxima on human skeletal and cardiac muscle cells. Toxicon, 233. 107250.

Lennox-Bulow, Danica, Smout, Michael, Loukas, Alex, and Seymour, Jamie (2023) Stonefish (Synanceia spp.) Ichthyocrinotoxins: An ecological review and prospectus for future research and biodiscovery. Toxicon, 236. 107329.

Ruangsuwast, Apisit, Smout, Michael J., Brindley, Paul J., Loukas, Alex, Laha, Thewarach, and Chaiyadet, Sujittra (2023) Tetraspanins from the liver fluke Opisthorchis viverrini stimulate cholangiocyte migration and inflammatory cytokine production. Folia Parasitologica, 70. 017.

Chaiyadet, Sujittra, Tangkawattana, Sirikachorn, Smout, Michael J., Ittiprasert, Wannaporn, Mann, Victoria H., Deenonpoe, Raksawan, Arunsan, Patpicha, Loukas, Alex, Brindley, Paul J., and Laha, Thewarach (2022) Knockout of liver fluke granulin, Ov-grn-1, impedes malignant transformation during chronic infection with Opisthorchis viverrini. PLoS Pathogens, 18 (9). e1010839.

Schmidt, Casey A., Cooke, Ira, Wilson, David T., Miller, David J., Peigneur, Steve, Tytgat, Jan, Field, Matthew, Takjoo, Rozita, Smout, Michael J., Loukas, Alex, and Daly, Norelle L. (2022) Newly Discovered Peptides from the Coral Heliofungia actiniformis Show Structural and Functional Diversity. Journal of Natural Products, 85 (7). pp. 1789-1798.

Chaiyadet, Sujittra, Sotillo, Javier, Krueajampa, Watchara, Thongsen, Sophita, Smout, Michael, Brindley, Paul J., Laha, Thewarach, and Loukas, Alex (2022) Silencing of Opisthorchis viverrini Tetraspanin Gene Expression Results in Reduced Secretion of Extracellular Vesicles. Frontiers in Cellular and Infection Microbiology, 12. 827521.

Phumrattanaprapin, Wuttipong, Pearson, Mark, Pickering, Darren, Tedla, Bemnet, Smout, Michael, Chaiyadet, Sujittra, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2021) Monoclonal antibodies targeting an opisthorchis viverrini extracellular vesicle tetraspanin protect hamsters against challenge infection. Vaccines, 9 (7). 740.

Adegboye, Oyelola, Field, Matt A., Kupz, Andreas, Pai, Saparna, Sharma, Dileep, Smout, Michael J., Wangchuk, Phurpa, Wong, Yide, and Loiseau, Claire (2021) Natural-product-based solutions for tropical infectious diseases. Clinical Microbiology Reviews, 34 (4). e00348-20.

Phumrattanaprapin, Wuttipong, Chaiyadet, Sujittra, Brindley, Paul J., Pearson, Mark, Smout, Michael J., Loukas, Alex, and Laha, Thewarach (2021) Orally administered Bacillus spores expressing an extracellular vesicle-derived tetraspanin protect hamsters against challenge infection with carcinogenic human liver fluke. Journal of Infectious Diseases, 223 (8). pp. 1445-1455.

Housley, David M., Pinyon, Jeremy L., Jonquieres, Georg von, Perera, Chamini J., Smout, Michael, Liddell, Michael J., Jennings, Ernest A., Wilson, David, and Housley, Gary D. (2020) Australian scorpion Hormurus waigiensis venom fractions show broad bioactivity through modulation of bio-impedance and cytosolic calcium. Biomolecules, 10 (4). 617.

Takjoo, Rozita, Wilson, David T., Bansal, Paramjit, Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2020) Folding of truncated granulin peptides. Biomolecules, 10 (8). 1152.

Mbanefo, Evaristus C., Agbo, Chinwike Terry, Zhao, Yuanlong, Lamanna, Olivia K., Thai, Kim H., Karinshak, Shannon E., Khan, Mohammad Afzal, Fu, Chi-Ling, Odegaard, Justin I., Saltikova, Irina V., Smout, Michael J., Pennington, Luke F., Nicolls, Mark R., Jardetzky, Theodore S., Loukas, Alex, Brindley, Paul J., Falcone, Franco H., and Hsieh, Michael H. (2020) IPSE, an abundant egg-secreted protein of the carcinogenic helminth Schistosoma haematobium, promotes proliferation of bladder cancer cells and angiogenesis. Infectious Agents and Cancer, 15. 63.

Arunsan, Patpicha, Chaidee, Apisit, Cochran, Christina J., Mann, Victoria H., Tanno, Toshihiko, Kumkhaek, Chutima, Smout, Michael J., Karinshak, Shannon E., Rodpai, Rutchanee, Sotillo, Javier, Loukas, Alex, Laha, Thewarach, Brindley, Paul J., and Ittiprasert, Wannaporn (2020) Liver fluke granulin promote extracellular vesicle-mediated crosstalk and cellular microenvironment conducive to cholangiocarcinoma. Neoplasia, 22 (5). pp. 203-216.

Arunsan, Patpicha, Ittiprasert, Wannaporn, Smout, Michael J., Cochran, Christina J., Mann, Victoria H., Chaiyadet, Sujittra, Karinshak, Shannon E., Sripa, Banchob, Young, Neil David, Sotillo, Javier, Loukas, Alex, Brindley, Paul J., and Laha, Thewarach (2019) Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity. eLife, 8. e41463.

Ritchie, Scott A., van den Hurk, Andrew F., Smout, Michael J., Staunton, Kyran M., and Hoffmann, Ary A. (2018) Mission accomplished? We need a guide to the ‘post release’ world of Wolbachia for Aedes-borne disease control. Trends in Parasitology, 34 (3). pp. 217-226.

Wangchuk, Phurpa, Apte, Simon H., Smout, Michael J., Groves, Penny L., Loukas, Alex, and Doolan, Denise L. (2018) Defined small molecules produced by Himalayan medicinal plants display immunomodulatory properties. International Journal of Molecular Sciences, 19 (11). 3490.

Yan, Hong-Bin, Smout, Michael J., Ju, Chuan, Folley, Anne E., Skinner, Danielle E., Mann, Victoria H., Loukas, Alex, Hu, Wei, Brindley, Paul J., and Rinaldi, Gabriel (2018) Developmental sensitivity in Schistosoma mansoni to puromycin to establish drug selection of transgenic schistosomes. Antimicrobial Agents and Chemotherapy, 62 (8). e02568-17.

Dastpeyman, Mohadeseh, Smout, Michael J., Wilson, David, Loukas, Alex, and Daly, Norelle L. (2018) Folding of granulin domains. Peptide Science, 110 (3). e24062.

Haugen, Brandon, Karinshak, Shannon E., Mann, Victoria H., Popratiloff, Anastas, Loukas, Alex, Brindley, Paul J., and Smout, Michael J. (2018) Granulin secreted by the food-borne liver fluke Opisthorchis viverrini promotes angiogenesis in human endothelial cells. Frontiers in Medicine, 5. 30.

Suttiprapa, Sutas, Sotillo, Javier, Smout, Michael, Suyapoh, Watcharapol, Chaiyadet, Sujittra, Tripathi, Timir, Laha, Thewarach, and Loukas, Alex (2018) Opisthorchis viverrini proteome and host-parasite interactions. In: UNSPECIFIED, (ed.) Advances in Parasitology. Advances in Parasitology, 102 . Elsevier, London, UK, pp. 45-72.

Neale, Vanessa, Smout, Michael J., and Seymour, Jamie E. (2018) Spine-bellied sea snake (Hydrophis curtus) venom shows greater skeletal myotoxicity compared with cardiac myotoxicity. Toxicon, 143. pp. 108-117.

Andreosso, Athena, Bansal, Paramjit S., Smout, Michael J., Wilson, David, Seymour, Jamie E., and Daly, Norelle L. (2018) Structural characterisation of predicted helical regions in the Chironex fleckeri CfTX-1 toxin. Marine Drugs, 16 (6). 201. pp. 1-12.

Dastpeyman, Mohadeseh, Bansal, Paramjit S., Wilson, David, Sotillo, Javier, Brindley, Paul J., Loukas, Alex, Smout, Michael J., and Daly, Norelle L. (2018) Structural variants of a liver fluke derived granulin peptide potently stimulate wound healing. Journal of Medicinal Chemistry, 61 (19). pp. 8746-8753.

Gangur, Alex N., Seymour, Jamie E., Liddell, Michael J., Wilson, David, Smout, Michael J., and Northfield, Tobin D. (2018) When is overkill optimal? Tritrophic interactions reveal new insights into venom evolution. Theoretical Ecology, 11 (2). pp. 141-149.

Sundaraneedi, Madhu K., Tedla, Bemnet A., Eichenberger, Ramon M., Becker, Luke, Pickering, Darren, Smout, Michael J., Rajan, Siji, Wangchuk, Phurpa, Keene, F. Richard, Loukas, Alex, Collins, J. Grant, and Pearson, Mark S. (2017) Polypyridylruthenium(II) complexes exert anti-schistosome activity and inhibit parasite acetylcholinesterases. PLoS Neglected Tropical Diseases, 11 (12). e0006134.

Gangur, Alexander, Smout, Michael, Liddell, Michael, Seymour, Jamie, Wilson, David, and Northfield, Tobin (2017) Changes in predator exposure, but not diet induce phenotypic plasticity in scorpion venom. Proceedings of the Royal Society of London Series B, Biological Sciences, 284 (1863).

Jin, Ai-Hua, Dekan, Zoltan, Smout, Michale J., Wilson, David, Dutertre, Sebastien, Vetter, Irina, Lewis, Richard J., Loukas, Alex, Daly, Norelle L., and Alewood, Paul F. (2017) Conotoxin Phi-MiXXVIIA from the superfamily G2 employs a novel cysteine framework that mimics granulin and displays anti-apoptotic activity. Angewandte Chemie International Edition, 56 (47). pp. 14973-14976.

Bansal, Paramjit S., Smout, Michael J., Wilson, David, Cobos Caceres, Claudia, Dastpeyman, Mohadeseh, Sotillo, Javier, Seifert, Julia, Brindley, Paul J., Loukas, Alex, and Daly, Norelle L. (2017) Development of a potent wound healing agent based on the liver fluke granulin structural fold. Journal of Medicinal Chemistry, 60 (10). pp. 4258-4266.

Barnett, Samantha, Saggiomo, Silvia, Smout, Michael, and Seymour, Jamie (2017) Heat deactivation of the stonefish Synanceia horrida venom – implications for first-aid management. Diving and Hyperbaric Medicine, 47 (3). pp. 155-158.

Chaiyadet, Sujittra, Smout, Michael, Laha, Thewarach, Sripa, Banchob, Loukas, Alex, and Sotillo, Javier (2017) Proteomic characterization of the internalization of Opisthorchis viverrini excretory/secretory products in human cells. Parasitology International, 66 (4). pp. 494-502.

Chaiyadet, Sujittra, Krueajampa, Watchara, Hipkaeo, Wiphawi, Plosan, Yada, Piratae, Supawadee, Sotillo, Javier, Smout, Michael, Sripa, Banchob, Brindley, Paul J., Loukas, Alex, and Laha, Thewarach (2017) Suppression of mRNAs encoding CD63 family tetraspanins from the carcinogenic liver fluke Opisthorchis viverrini results in distinct tegument phenotypes. Scientific Reports, 7. 14342.

Wangchuk, Phurpa, Pearson, Mark S., Giacomin, Paul R., Becker, Luke, Sotillo, Javier, Pickering, Darren, Smout, Michael J., and Loukas, Alex (2016) Compounds derived from the Bhutanese daisy, Ajania nubigena, demonstrate dual anthelmintic activity against Schistosoma mansoni and Trichuris muris. PLOS Neglected Tropical Diseases, 10 (8). e0004908. pp. 1-18.

Wangchuk, Phurpa, Giacomin, Paul R., Pearson, Mark S., Smout, Michael J., and Loukas, Alex (2016) Identification of lead chemotherapeutic agents from medicinal plants against blood flukes and whipworms. Scientific Reports, 6. 32101. pp. 1-10.

Rinaldi, Gabriel, Loukas, Alex, Brindley, Paul J., Irelan, Jeff T., and Smout, Michael J. (2015) Viability of developmental stages of Schistosoma mansoni quantified with xCELLigence worm real-time motility assay (xWORM). International Journal for Parasitology: Drugs and Drugs Resistance, 5 (3). pp. 141-148.

Smout, Michael J., Sotillo, Javier, Laha, Thewarach, Papatpremsiri, Atiroch, Rinaldi, Gabriel, Pimenta, Rafael N., Chan, Lai Yue, Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Giacomin, Paul R., Moran, Corey S., Golledge, Jonathan, Daly, Norelle, Sripa, Banchob, Mulvenna, Jason P., Brindley, Paul J., and Loukas, Alex (2015) Carcinogenic parasite secretes growth factor that accelerates wound healing and potentially promotes neoplasia. PLoS Pathogens, 11 (10). e100520. pp. 1-20.

Chaiyadet, Sujittra, Smout, Michael, Johnson, Michael, Whitchurch, Cynthia, Turnbull, Lynne, Kaewkes, Sasithorn, Sotillo, Javier, Loukas, Alex, and Sripa, Banchob (2015) Excretory/secretory products of the carcinogenic liver fluke are endocytosed by human cholangiocytes and drive cell proliferation and IL6 production. International Journal for Parasitology, 45 (12). pp. 773-781.

Rinaldi, Gabriel, Yan, Hongbin, Nacif-Pimenta, Rafael, Matchimakul, Pitchaya, Bridger, Joanna, Mann, Victoria H., Smout, Michael J., Brindley, Paul J., and Knight, Matty (2015) Cytometric analysis, genetic manipulation and antibiotic selection of the snail embryonic cell line Bge from Biomphalaria glabrata, the intermediate host of Schistosoma mansoni. International Journal for Parasitology, 45 (8). pp. 527-535.

Chaiyadet, Sujittra, Sotillo, Javier, Smout, Michael, Cantacessi, Cinzia, Jones, Malcolm K., Johnson, Michael S., Turnbull, Lynne, Whitchurch, Cynthia B., Potriquet, Jeremy, Laohaviroj, Marut, Mulvenna, Jason, Brindley, Paul J., Bethony, Jeffrey M., Laha, Thewarach, Sripa, Banchob, and Loukas, Alex (2015) Carcinogenic liver fluke secretes extracellular vesicles that promote cholangiocytes to adopt a tumorigenic phenotype. Journal of Infectious Diseases, 212 (10). pp. 1636-1645.

Papatpremsiri, Atiroch, Smout, Michael J., Loukas, Alex, Brindley, Paul J., Sripa, Banchob, and Laha, Thewarach (2015) Suppression of Ov-grn-1 encoding granulin of Opisthorchis viverrini inhibits proliferation of biliary epithelial cells. Experimental Parasitology, 148. pp. 17-23.

Koeberl, Martina, Kamath, Sandip D., Saptarshi, Shruti R., Smout, Michael J., Rolland, Jennifer M., O'Hehir, Robyn E., and Lopata, Andreas L. (2014) Auto-induction for high yield expression of recombinant novel isoallergen tropomyosin from King prawn (Melicertus latisulcatus) for improved diagnostics and immunotherapeutics. Journal of Immunological Methods, 415. pp. 6-16.

Andreosso, Athena, Smout, Michael J., and Seymour, Jamie E. (2014) Dose and time dependence of box jellyfish antivenom. Journal of Venomous Animals and Toxins including Tropical Diseases, 20. 34. pp. 1-5.

Zeraik, Ana E., Galkin, Vitold E., Rinaldi, Gabriel, Garratt, Richard C., Smout, Michael J., Loukas, Alex, Mann, Victoria H., Araujo, Ana P.U., DeMarco, Ricardo, and Brindley, Paul J. (2014) Reversible paralysis of Schistosoma mansoni by forchlorfenuron, a phenylurea cytokinin that affects septins. International Journal for Parasitology, 44 (8). pp. 523-531.

Smout, Michael (2014) Understanding the causes of bile duct liver cancer. Voices, 5 June 2014.

Chaousis, Stephanie, Smout, Michael, Wilson, David, Loukas, Alex, Mulvenna, Jason, and Seymour, Jamie (2014) Rapid short term and gradual permanent cardiotoxic effects of vertebrate toxins from Chironex fleckeri (Australian box jellyfish) venom. Toxicon, 80. pp. 17-26.

You, Hong, McManus, Donald P., Hu, Wei, Smout, Michael J., Brindley, Paul J., and Gobert, Geoffrey N. (2013) Transcriptional responses of in vivo praziquantel exposure in schistosomes identifies a functional role for calcium signalling pathway member CamKII. PLoS Pathogens, 9 (3). e1003254.

Sripa, Banchob, Brindley, Paul J., Mulvenna, Jason, Laha, Thewarach, Smout, Michael J., Mairiang, Eimorn, Bethony, Jeffrey M., and Loukas, Alex (2012) The tumorigenic liver fluke Opisthorchis viverrini - multiple pathways to cancer. Trends in Parasitology, 28 (10). pp. 395-407.

Smout, Michael J., Mulvenna, Jason P., Jones, Malcolm K., and Loukas, Alex (2011) Expression, refolding and purification of Ov-GRN-1, a granulin-like growth factor from the carcinogenic liver fluke, that causes proliferation of mammalian host cells. Protein Expression and Purification, 79 (2). pp. 263-270.

Smout, Michael J., Sripa, Banchob, Laha, Thewarach, Mulvenna, Jason, Gasser, Robin B. , Young, Neil D., Bethony, Jeffrey M., Brindley, Paul J., and Loukas, Alex (2011) Infection with the carcinogenic human liver fluke, Opisthorchis viverrini. Molecular BioSystems, 7 (5). pp. 1367-1375.

Smout, Michael J., Kotze, Andrew C., McCarthy, James S., and Loukas, Alex (2010) A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility. PLoS Neglected Tropical Disease, 4 (11). e885. pp. 1-10.

Mulvenna, Jason, Sripa, Banchob, Brindley, Paul J., Gorman, Jeffrey, Jones, Malcolm K., Colgrave, Michelle L., Jones, Alun, Nawaratna, Sujeevi, Laha, Thewarach, Suttiprapa, Sutas, Smout, Michael J., and Loukas, Alex (2010) The secreted and surface proteomes of the adult stage of the carcinogenic human liver fluke Opisthorchis viverrini. Proteomics, 10 (5). pp. 1063-1078.

Smout, Michael J., Laha, Thewarach, Mulvenna, Jason, Sripa, Banchob, Suttiprapa, Sutas, Jones, Alun, Brindley, Paul J., and Loukas, Alex (2009) A granulin-like growth factor secreted by the carcinogenic liver fluke, Opisthorchis viverrini, promotes proliferation of host cells. PLoS Pathogens, 5 (10). e1000611. pp. 1-16.

Sripa, Banchob, Kaewkes, Sasithorn, Sithithaworn, Paiboon, Mairiang, Eimorn, Laha, Thewarach, Smout, Michael, Pairojkul, Chawalit, Bhudhisawasdi, Vajaraphongsa, Tesana, Smarn, Thinkamrop, Bandit, Bethony, Jeffrey M., Loukas, Alex, and Brindley, Paul J. (2007) Liver fluke induces Cholangiocarcinoma. PLoS Medicine, 4 (7). 201. pp. 1148-1155.

Laha, Thewarach, Pinlaor, Porntip, Mulvenna, Jason, Sripa, Banchob, Sripa, Manop, Smout, Michael J., Gasser, Robin B., Brindley, Paul J., and Loukas, Alex (2007) Gene discovery for the carcinogenic human liver fluke, Opisthorchis viverrini. BMC Genomics, 8. 189. pp. 1-15.

Bethony, Jeffrey, Loukas, Alex, Smout, Michael, Brooker, Simon, Mendez, Susana, Plieskatt, Jordan, Goud, Gaddam, Bottazzi, Maria Elena, Zhan, Bin, Wang, Yan, Williamson, Angela, Lustigman, Sara, Correa-Oliveira, Rodrigo, Xiao, Shuhua, and Hotez, Peter J. (2005) Antibodies against a secreted protein from hookworm larvae reduce the intensity of hookworm infection in humans and vaccinated laboratory animals. FASEB Journal, 19 (12). pp. 1743-1745.

Morton, Craig J., Cameron, Rachel, Lawrence, Lynne J., Lin, Bo, Lowe, Melinda, Luttick, Angela, Mason, Anthony, McKimm-Breschkin, Jenny, Parker, Michael W., Ryan, Jane, Smout, Michael, Sullivan, Jayne, Tucker, Simon P., and Young, Paul R. (2003) Structural characterization of respiratory syncytial virus fusion inhibitor escape mutants: homology model of the F protein and a syncytium formation assay. Virology, 311 (2). pp. 275-288.

Smyth, Danielle, McManus, Donald P., Smout, Michael J., Laha, Thewarach, Zhang, Wenbao, and Loukas, Alex (2003) Isolation of cDNAs encoding secreted and transmembrane proteins from Schistosoma mansoni by a signal sequence trap method. Infection and Immunity, 71 (5). pp. 2548-2554.

laha, Thewarch, Brindley, Paul J., Smout, Michael J., Verity, Christiana K., McManus, Donald P., and Loukas, Alex (2002) Reverse transcriptase activity and untranslated region sharing of a new RTE-like, non-long terminal repeat retrotransposon from the human blood fluke, Schistosoma japonicum. International Journal for Parasitology, 32 (9). pp. 1163-1174.