Bourquin, Rebecca Ashleigh (2023) Development of a high-throughput HIV-1 integrase drug screening platform. Masters (Research) thesis, James Cook University.

PDF (Thesis) Restricted to Repository staff only until 2 August 2024.

Abstract

Rebecca Bourquin developed a drug screening platform for HIV-1 integrase. She characterised fluorescent protein-tagged integrase and used this to develop a simple quantitative polymerase chain reaction assay that can be used to find new therapeutics for HIV-1 treatment. This assay will be used for compound library screening in the future.

Item ID:	80973
Item Type:	Thesis (Masters (Research))
Keywords:	HIV-1, integrase, IN, human immunodeficiency virus, HIV, AIDS, drug resistance, fluorescent protein-tagged integrase, polymerase chain reaction assay
Copyright Information:	Copyright © 2023 Rebecca Ashleigh Bourquin
Additional Information:	Embargoed until 2 August 2024
Date Deposited:	07 Nov 2023 03:27
FoR Codes:	32 BIOMEDICAL AND CLINICAL SCIENCES > 3204 Immunology > 320406 Immunogenetics (incl. genetic immunology) @ 30% 31 BIOLOGICAL SCIENCES > 3101 Biochemistry and cell biology > 310106 Enzymes @ 30% 31 BIOLOGICAL SCIENCES > 3101 Biochemistry and cell biology > 310109 Proteomics and intermolecular interactions (excl. medical proteomics) @ 40%
SEO Codes:	20 HEALTH > 2001 Clinical health > 200101 Diagnosis of human diseases and conditions @ 40% 20 HEALTH > 2001 Clinical health > 200105 Treatment of human diseases and conditions @ 30% 20 HEALTH > 2004 Public health (excl. specific population health) > 200412 Preventive medicine @ 30%
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