Lihouidine, a novel spiro polycyclic aromatic alkaloid from the marine sponge Suberea n. sp (Aplysinellidae, Verongida)

Bowden, Bruce F., McCool, Brian J., and Willis, Richard H. (2004) Lihouidine, a novel spiro polycyclic aromatic alkaloid from the marine sponge Suberea n. sp (Aplysinellidae, Verongida). Journal of Organic Chemistry, 69 (23). pp. 7791-7793.

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Abstract

An investigation of a new species of sponge from the genus Suberea collected at Lihou Reef in the Coral Sea afforded lihouidine, an unprecedented cytotoxic Spiro nonacyclic polyaromatic alkaloid. The structure of the alkaloid, which was racemic, was determined by a combination of ID and 2D NMR techniques and single-crystal X-ray structural analysis.

Item ID: 561
Item Type: Article (Refereed Research - C1)
Keywords: lihouidine, Porifera, Aplysinellidae, Suberea, bromotyrosine alkaloids, aaptamine, metabolites, Lihou Reef
Additional Information:

© 2004 American Chemical Society : The contents of this journal can be freely accessed online via the ACS web page 12 months after publication. Use hypertext link above to access the ACS website.

ISSN: 1520-6904
Date Deposited: 10 May 2007
FoR Codes: 03 CHEMICAL SCIENCES > 0304 Medicinal and Biomolecular Chemistry > 030499 Medicinal and Biomolecular Chemistry not elsewhere classified @ 50%
03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030505 Physical Organic Chemistry @ 50%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
Citation Count from Web of Science Web of Science 13
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