Short report: surveillance and molecular characterization of group A rotaviruses in Goroka, Papua New Guinea

Horwood, Paul Francis, Luang-Suarkia, Dagwin, Bebes, Sauli, Boniface, Karen, Datta, Siddhartha Sankar, Siba, Peter Max, and Kirkwood, Carl Dunn (2012) Short report: surveillance and molecular characterization of group A rotaviruses in Goroka, Papua New Guinea. American Journal of Tropical Medicine and Hygiene, 87 (6). pp. 1145-1148.

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DOI: 10.4269/ajtmh.2012.12-0234

View at Publisher Website: http://dx.doi.org/10.4269/ajtmh.2012.12-...

Abstract

In this study, we investigated the molecular epidemiology of group A rotaviruses in cases of acute gastroenteritis in Goroka, Papua New Guinea. From April 2008 through November 2010, 813 diarrheal stool samples were collected from children < 5 years of age hospitalized with acute gastroenteritis. Rotavirus antigen was detected in 31.2% of samples using a commercial enzyme-linked immunosorbent assay. Genotyping revealed the presence of the globally circulating strains G1P[8] (50.0%), G3P[8] (23.0%), and G2P[4] (8.2%). The globally emerging strains G9 and G12 were detected in 1.2% and 6.1% of samples, respectively. Mixed infections were detected in a high proportion of samples (11.9%), with 9.0% and 3.7% of samples displaying multiple G and P genotypes, respectively.


Item ID:	47273
Item Type:	Article (Research - C1)
ISSN:	1476-1645
Funders:	World Health Organisation (WHO), National Health and Medical Research Council of Australia (NHMRC)
Projects and Grants:	WHO Western Pacific Rotavirus Surveillance Network, NHMRC CDA Fellowship 609347
Date Deposited:	22 Feb 2017 00:26
FoR Codes:	11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110309 Infectious Diseases @ 100%
SEO Codes:	92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920109 Infectious Diseases @ 100%
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