High concentration potassium permanganate eliminates protein and particle contamination of the reusable Classic™ laryngeal mask airway

Laupau, W., Brimacombe, J., Richards, E., and Keller, C. (2006) High concentration potassium permanganate eliminates protein and particle contamination of the reusable Classic™ laryngeal mask airway. Anaesthesia, 61 (6). pp. 524-527.

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Abstract

In this three-stage study, we test the hypothesis that supplementary cleaning with potassium permanganate ≥4 mg.l−1 eliminates protein and particle contamination from the reusable Classic™ laryngeal mask airway. The first stage involved supplementary cleaning of 70 1 × 1 cm segments from deliberately contaminated laryngeal mask airways using potassium permanganate at 0, 2, 4, 8, 16, 32 and 64 mg.l−1 and testing for protein staining. This showed that the lowest concentration required to eliminate protein contamination was 8 mg.l−1. The second stage involved supplementary cleaning of 50 used laryngeal mask airways with either potassium permanganate 8 mg.l−1 or saline and testing for protein staining. This showed that protein contamination was lower in the potassium permanganate group (p < 0.00001): all laryngeal mask airways in the control group and none in the potassium permanganate group were contaminated. The third stage involved scanning electron microscopic examination of 1 × 1 cm segments from three laryngeal mask airways used in the control group, three from the potassium permanganate group, plus three brand new laryngeal mask airways. The mean density of ≥1 μm surface particles was lower in the potassium permanganate 8 mg.l−1 than the control group (21 vs. 121 .cm−2, p < 0.0001) and was similar to brand new laryngeal mask airways (24 .cm−2). We conclude that supplementary cleaning with potassium permanganate 8 mg.l−1 eliminates protein deposits from reusable laryngeal mask airways and reduces particle contamination to similar levels to brand new laryngeal mask airways.

Item ID: 3757
Item Type: Article (Refereed Research - C1)
Keywords: anaesthesia; laryngeal mask airway; potassium permanganate
ISSN: 0003-2409
Date Deposited: 26 Nov 2009 04:58
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1101 Medical Biochemistry and Metabolomics > 110106 Medical Biochemistry: Proteins and Peptides (incl Medical Proteomics) @ 34%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110301 Anaesthesiology @ 33%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110302 Clinical Chemistry (diagnostics) @ 33%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 51%
92 HEALTH > 9205 Specific Population Health (excl. Indigenous Health) > 920504 Occupational Health @ 49%
Citation Count from Web of Science Web of Science 4
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