Renal parenchymal thickness as a measure of renal growth in low-birth-weight infants versus normal-birth-weight infants

Brennan, Sonja, and Kandasamy, Yogavijayan (2013) Renal parenchymal thickness as a measure of renal growth in low-birth-weight infants versus normal-birth-weight infants. Ultrasound in Medicine and Biology, 39 (12). pp. 2315-2320.

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Abstract

Low birth weight (LBW, <2500 g) infants have a reduced number of glomeruli and nephrons and, therefore, smaller kidneys. The purpose of this pilot study was to determine whether renal parenchymal thickness might be a better indicator of renal growth. We carried out a pilot study over 12 mo to determine whether renal parenchymal thickness could be used to detect differences in renal growth between LBW and normal birth weight (NBW, 2500–4500 g) infants. Thirty-eight term infants (12 LBW and 26 NBW) underwent renal ultrasound. Parenchymal thickness, length, transverse diameter and antero-posterior diameter were measured. Mean renal parenchymal thickness was significantly lower in LBW infants than in NBW infants. Renal parenchymal thickness was closely correlated with an increase in renal volume (r = 0.76, p < 0.0001). Renal parenchymal thickness is a single measurement that could potentially be a more useful and accurate approach to monitoring renal growth in growth-restricted infants than renal volume.

Item ID: 36541
Item Type: Article (Research - C1)
ISSN: 1879-291X
Keywords: renal parenchymal thickness; low birth weight; renal growth; nephron number; kidney; ultrasound; renal volume
Date Deposited: 16 Dec 2014 00:51
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111403 Paediatrics @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920199 Clinical Health (Organs, Diseases and Abnormal Conditions) not elsewhere classified @ 100%
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