Parallel Microflow Photochemistry: Process Optimization, Scale-up, and Library Synthesis

Yavorskyy, Alexander, Shvydkiv, Oksana, Hoffmann, Norbert, Nolan, Kieran, and Oelgemoeller, Michael (2012) Parallel Microflow Photochemistry: Process Optimization, Scale-up, and Library Synthesis. Organic Letters, 14 (17). pp. 4342-4345.

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Abstract

A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5H)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis.

Item ID: 23358
Item Type: Article (Refereed Research - C1)
ISSN: 1523-7052
Date Deposited: 09 Sep 2012 23:17
FoR Codes: 03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030503 Organic Chemical Synthesis @ 50%
03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030505 Physical Organic Chemistry @ 30%
03 CHEMICAL SCIENCES > 0305 Organic Chemistry > 030504 Organic Green Chemistry @ 20%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970103 Expanding Knowledge in the Chemical Sciences @ 100%
Citation Count from Web of Science Web of Science 2
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