Pharmaceutical excipients: where do we begin?

Haywood, Alison, and Glass, Beverley (2011) Pharmaceutical excipients: where do we begin? Australian Prescribing, 34 (4). pp. 112-114.

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Abstract

Excipients have been defined in many ways, including as inert substances used as vehicles and diluents for drugs. The problem with this definition is that in recent years excipients have proved to be anything but inert, not only possessing the ability to react with other ingredients in the formulation, but also to cause adverse and hypersensitivity reaction in patients. These range from a mild rash to a potentially life-threatening reaction. Different brands of the same drug may contain different excipients, especially preservatives and colourants. The Comsumer Medicines Information provides a list of excipients, and information on the safety of individual excipients can be found in drug reference guides.

Item ID: 20012
Item Type: Article (Short Note)
Keywords: adverse reactions, drug labelling, inactive ingredients, hypersensitivity
ISSN: 0312-8008
Date Deposited: 29 Feb 2012 06:27
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1115 Pharmacology and Pharmaceutical Sciences > 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
Citation Count from Web of Science Web of Science 2
Downloads: Total: 2
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