Vitamin D status of adults from tropical Australia determined using two different laboratory assays: implications for public health messages

Nowak, Madeleine, Harrison, Simone L., Buettner, Petra G., Kimlin, Michael, Porter, David, Kennedy, Lee, and Speare, Rick (2011) Vitamin D status of adults from tropical Australia determined using two different laboratory assays: implications for public health messages. Photochemistry and Photobiology, 87 (4). pp. 935-943.

[img] PDF (Published Version) - Published Version
Restricted to Repository staff only

View at Publisher Website: http://dx.doi.org/10.1111/j.1751-1097.20...

Abstract

We measured serum 25 hydroxyvitamin D [25(OH)D] levels of ambulatory adults in tropical Australia to determine whether it is appropriate to continue promoting sun-safety in this population. In August 2006 (winter), self-administered questionnaires were completed by 145 Meals-on-Wheels volunteers (49.3% male; mean age 57.8 ± 14.7 years; 76.6% response) from Townsville, Queensland (Latitude 19oS). Serum 25(OH)D was analyzed using two common assays. Mean levels were 68.3 (SD ± 18.7; range 26–142) by DiaSorin Radioimmunoassay and 83.0 (SD ± 30.8; range 30–184) by DiaSorin Liaison® one. No participants were 25(OH)D deficient (<25 nmol L−1). Nine participants (6.2%) had 25(OH)D levels between 25 and 50 nmol L−1 (insufficient), by both methods (seven with a BMI ≥ 25). Twenty-eight participants (19.3%) had one result in the insufficient range and the other in the adequate range. Thus, almost all of these free-living adults in tropical Australia had adequate vitamin D levels at the end of winter. There was poor agreement between the two 25(OH)D assays. These results suggest it is appropriate to continue promoting sun-safe messages to the ambulatory Caucasian adult population of North Queensland, which has an extremely high incidence of skin cancer. The lack of agreement between the two assays is a concern. Few doctors are aware of this measurement issue.

Item ID: 19102
Item Type: Article (Refereed Research - C1)
ISSN: 1751-1097
Date Deposited: 07 Nov 2011 04:56
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111716 Preventive Medicine @ 100%
SEO Codes: 92 HEALTH > 9204 Public Health (excl. Specific Population Health) > 920412 Preventive Medicine @ 100%
Citation Count from Web of Science Web of Science 2
Downloads: Total: 3
More Statistics

Actions (Repository Staff Only)

Item Control Page Item Control Page