Malignant range elevation of serum chromogranin A due to inadvertent use of proton pump inhibitor in a subject with pancreatic incidentaloma

Malabu, Usman, Karamatic, Rozemary, Mahy, Gillian, and Sangla, Kunwarjit Singh (2011) Malignant range elevation of serum chromogranin A due to inadvertent use of proton pump inhibitor in a subject with pancreatic incidentaloma. Case Reports in Endocrinology. pp. 1-3.

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Abstract

We present a case of highly elevated tenfold rise of serum chromogranin A in a young, morbidly obese, hypertensive female being investigated for pancreatic mass, weight loss, and elevated ESR. Following extensive noninvasive investigations, an ultrasound-guided pancreatic biopsy confirmed benign haemorrhagic cyst. A clue to the etiology of the hyperchromogranin A was the elevated serum gastrin level leading to suspicion of proton pump inhibitor administration confirmed by admittance to its use. Withdrawal of the medication led to dramatic resolution of the neuroendocrine tumor marker.

Item ID: 18879
Item Type: Article (Case Study)
Additional Information:

Copyright © 2011 Usman HammawaMalabu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

ISSN: 2090-651X
Date Deposited: 25 Oct 2011 00:34
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110306 Endocrinology @ 100%
SEO Codes: 92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920106 Endocrine Organs and Diseases (excl. Diabetes) @ 100%
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