UTIs: Molecular scrutiny. Is there zoonotic potential?
Squires, Richard A. (2006) UTIs: Molecular scrutiny. Is there zoonotic potential? In: Presentations from the 49th Annual Congress of British Small Animal Veterinary Association, pp. 1-2. From: 49th Annual Congress of British Small Animal Veterinary Association, 20-23 April 2006, Birmingham, UK.
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Mention the word 'zoonosis' in the context of exposure to companion animal urine and most veterinarians would quickly think of canine leptospirosis. Brucellosis and Q fever might also come to mind. However, it would be a surprise to many veterinarians to learn that canine and feline urinary Escherichia coli strains have, in recent years, been implicated as potentially zoonotic.
Early on, interest focused upon the fact that E. coli strains obtained from humans (mostly women) and companion animals with urinary tract infections (UTI) shared many, identical virulence factor genes. Possession of these genes, and expression of their protein products, enable a small subset of all E. coli strains to colonize, persist and multiply within the host's urinary tract. It was argued that–since many canine and feline urinary E. coli strains have virulence factors relevant to gaining entry and persisting within human urinary tracts–dogs and cats should be viewed as potential reservoirs of uropathogenic E. coli for humans.
|Item Type:||Conference Item (Presentation)|
|Date Deposited:||27 Sep 2011 04:29|
|FoR Codes:||07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070706 Veterinary Medicine @ 100%|
|SEO Codes:||86 MANUFACTURING > 8609 Veterinary Pharmaceutical Products > 860902 Veterinary Diagnostics @ 50%
92 HEALTH > 9201 Clinical Health (Organs, Diseases and Abnormal Conditions) > 920120 Zoonoses @ 50%