The burden of kidney disease in Indigenous children of Australia and New Zealand, epidemiology, antecedent factors and progression to chronic kidney disease

White, Andrew, Wong, William, Sureshkumur, Premala, and Singh, Gurmeet (2010) The burden of kidney disease in Indigenous children of Australia and New Zealand, epidemiology, antecedent factors and progression to chronic kidney disease. Journal of Paediatrics and Child Health, 46 (9). pp. 504-509.

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Abstract

Aims: To review and present the most important issues related to kidney disease in Aboriginal, Torres Strait Islander,Maori and Pacific Islander children from Australia and New Zealand.

Methods: A review of medical literature about: 1. incidence of kidney disease in Indigenous children in Australia and New Zealand, especially where rates are different from the general populations, 2. factors in early life which increase risk for chronic kidney disease in adult life, and 3. early identification and primary and secondary interventions in childhood which may prevent chronic kidney disease in adults.

Results: Kidney diseases, both acute and chronic are more common in Maori, Pacific Islander, Australian Aboriginal and Torres Strait Islander people. The reasons are multiple and include genetic, environmental and socio-economic factors. In childhood post streptococcal glomerulonephritis, haemolytic uraemic syndrome, renal stones and acute kidney injury all occur at higher frequency in at least some of the Indigenous populations. Chronic kidney disease CKD occurs more commonly, and at a younger age in Indigenous than non Indigenous people. Factors involved may include reduced nephron endowment at birth, and subsequent insults including nephritis, obesity, and early onset type 2 diabetes, as well as underlying socioeconomic and environmental determinants.

Conclusion: A lifecourse understanding allows one to conceptualise multiple risk factors and target interventions.

Item ID: 15005
Item Type: Article (Refereed Research - C1)
Keywords: general paediatrics; international child health; nephrology/renal
ISSN: 1440-1754
Date Deposited: 01 Dec 2010 05:09
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1114 Paediatrics and Reproductive Medicine > 111403 Paediatrics @ 50%
11 MEDICAL AND HEALTH SCIENCES > 1103 Clinical Sciences > 110312 Nephrology and Urology @ 50%
SEO Codes: 92 HEALTH > 9203 Indigenous Health > 920301 Aboriginal and Torres Strait Islander Health - Determinants of Health @ 40%
92 HEALTH > 9205 Specific Population Health (excl. Indigenous Health) > 920501 Child Health @ 20%
92 HEALTH > 9203 Indigenous Health > 920304 Maori Health - Determinants of Health @ 40%
Citation Count from Web of Science Web of Science 6
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