Experimental Trypanosoma evansi infection in the goat I: clinical signs and clinical pathology

Dargantes, A.P., Reid, S., and Copeman, D.B. (2005) Experimental Trypanosoma evansi infection in the goat I: clinical signs and clinical pathology. Journal of Comparative Pathology, 133 (4). pp. 261-266.

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Abstract

A strain of Trypanosoma evansi isolated from an equine case of surra in Mindanao, Philippines was used to infect intravenously two groups (A and B) of five male goats aged 8–10 months. Animals of groups A and B received 5000 and 50 000 trypanosomes, respectively, and five further animals (group C) served as uninfected controls. Four of the 10 infected goats died 8–78 days after inoculation. Group C goats gained weight (mean 22.8 g/day) while infected goats in groups A and B lost weight (means of 21.4 and 45.0 g/day, respectively). Parasitaemia fluctuated regularly between peaks and troughs, with repeated periods of about 6 days during which no trypanosomes were detected in the blood. Clinical signs and clinico-pathological changes in infected goats were not pathognomonic in the absence of parasites in the blood, and leucocytosis was not a reliable indicator of infection. It was concluded that in endemic areas fluctuating fever, progressive emaciation, anaemia, coughing, testicular enlargement and diarrhoea are suggestive of surra; confirmation, however, may necessitate examination of blood every few days for trypanosomes, and possibly other diagnostic tests.

Item ID: 14034
Item Type: Article (Refereed Research - C1)
Keywords: goat; parasitic infection; surra; Trypanosoma evansi
ISSN: 1532-3129
Date Deposited: 23 Nov 2010 04:23
FoR Codes: 07 AGRICULTURAL AND VETERINARY SCIENCES > 0707 Veterinary Sciences > 070709 Veterinary Pathology @ 100%
SEO Codes: 83 ANIMAL PRODUCTION AND ANIMAL PRIMARY PRODUCTS > 8303 Livestock Raising > 830399 Livestock Raising not elsewhere classified @ 100%
Citation Count from Web of Science Web of Science 6
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