Phospholipase A2 in Cnidaria

Nevalainen, Timo J., Peuravuori, Heikki J., Quinn, Ronald J., Llewellyn, Lyndon E., Benzie, John A.H., Fenner, Peter J., and Winkel, Ken D. (2004) Phospholipase A2 in Cnidaria. Comparative Biochemistry and Physiology-Part B: biochemistry & molecular biology, 139 (4). pp. 731-735.

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Abstract

Phospholipase A2 (PLA2) is an enzyme present in snake and other venoms and body fluids. We measured PLA2 catalytic activity in tissue homogenates of 22 species representing the classes Anthozoa, Hydrozoa, Scyphozoa and Cubozoa of the phylum Cnidaria. High PLA2 levels were found in the hydrozoan fire coral Millepora sp. (median 735 U/g protein) and the stony coral Pocillopora damicornis (693 U/g) that cause skin irritation upon contact. High levels of PLA2 activity were also found in the acontia of the sea anemone Adamsia carciniopados (293 U/g). Acontia are long threads containing nematocysts and are used in defense and aggression by the animal. Tentacles of scyphozoan and cubozoan species had high PLA2 activity levels: those of the multitentacled box jellyfish Chironex fleckeri contained 184 U/g PLA2 activity. The functions of cnidarian PLA2 may include roles in the capture and digestion of prey and defense of the animal. The current observations support the idea that cnidarian PLA2 may participate in the sting site irritation and systemic envenomation syndrome resulting from contact with cnidarians.

Item ID: 13864
Item Type: Article (Refereed Research - C1)
Keywords: Australia; Cnidaria; Phospholipase A2;
ISSN: 1879-1107
Date Deposited: 17 Dec 2010 04:53
FoR Codes: 11 MEDICAL AND HEALTH SCIENCES > 1117 Public Health and Health Services > 111799 Public Health and Health Services not elsewhere classified @ 100%
SEO Codes: 92 HEALTH > 9299 Other Health > 929999 Health not elsewhere classified @ 100%
Citation Count from Web of Science Web of Science 44
Downloads: Total: 1
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