Mitochondrial genomes of human helminths and their use as markers in population genetics and phylogeny

Le, Thanh H., Blair, David, and McManus, Donald P. (2000) Mitochondrial genomes of human helminths and their use as markers in population genetics and phylogeny. Acta Tropica, 77 (3). pp. 243-256.

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Abstract

To date, over 100 complete metazoan mitochondrial (mt) genomes of different phyla have been reported. Here, we briefly summarise mt gene organisation in the Metazoa and review what is known of the mt genomes of nematodes and flatworms parasitic in humans. The availability of complete or almost complete mtDNA sequences for several parasitic helminths provides a rich source of genetic markers for phylogenetic analysis and study of genetic variability in helminth groups. Examples of the application of mtDNA in studies on Ascaris, Onchocerca, Schistosoma, Fasciola, Paragonimus, Echinostoma, Echinococcus and Taenia are described.

Item ID: 12730
Item Type: Article (Refereed Research - C1)
Keywords: Ascaris; mitochondrial DNA; mitochondrial genes; mitochondrion; Onchocerca; parasitic helminths; Onchocerca; Schistosoma; Fasciola; Paragonimus; Echinostoma; Echinococcus; Taenia
ISSN: 1873-6254
Date Deposited: 14 Dec 2010 02:27
FoR Codes: 06 BIOLOGICAL SCIENCES > 0603 Evolutionary Biology > 060399 Evolutionary Biology not elsewhere classified @ 100%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 100%
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