Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers

Khatkar, M.S., Zenger, K.R., Cavanagh, J.A.L., Hawken, R.J., Hobbs, M., Barris, W., Thomson, P.C., Nicholas, F.W., Tier, B., and Raadsma, H.W. (2007) Extent of linkage disequilibrium and haplotype blocks in bovine genome using high density SNP markers. In: Proceedings of the Association for the Advancement of Animal Breeding and Genetics (17), pp. 215-218. From: 17th AAABG Conference 2007, 23-26 September 2007, Armidale, NSW, Australia.

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Abstract

A haplotype block map of the bovine genome was constructed based on the analysis of 15,036 SNPs on 1,000 un-related bulls. This map identified a total of 727 haplotype blocks consisting of three or more SNPs. These blocks have a mean length of 69.7 kb and cover 2.2 % of the length of all autosomes. This analysis suggested that approximately 250,000 SNPs would be required to prepare a complete haplotype block map of the bovine genome with 75,000 tag SNPs.

Item ID: 10143
Item Type: Conference Item (Refereed Research Paper - E1)
Keywords: quantitative genetics; dairy cattle; selective breeding; genetics; QTL; genomics
Additional Information:

Conference theme "Genetic Improvement - Making it Happen"

ISBN: 978-1-921208-13-3
ISSN: 1328-3227
Date Deposited: 20 Jul 2010 03:53
FoR Codes: 06 BIOLOGICAL SCIENCES > 0604 Genetics > 060408 Genomics @ 80%
07 AGRICULTURAL AND VETERINARY SCIENCES > 0702 Animal Production > 070201 Animal Breeding @ 20%
SEO Codes: 97 EXPANDING KNOWLEDGE > 970107 Expanding Knowledge in the Agricultural and Veterinary Sciences @ 50%
97 EXPANDING KNOWLEDGE > 970106 Expanding Knowledge in the Biological Sciences @ 50%
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